PRURITUS IN CHRONIC CHOLESTATIC LIVER DISEASES
نویسندگان
چکیده
منابع مشابه
Neuromediators for cholestatic pruritus
Cholestatic pruritus is one of the most common complaints in patients with liver diseases and intraor posthepatic cholestasis. The mechanisms of cholestatic pruritus remain poorly understood although multiple factors are considered to participate in the pathogenesis of cholestatic pruritus. Recent exciting studies have discovered several G-protein coupled receptors (GPCRs) and endogenous chemic...
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Cholestatic liver diseases are characterized by blockade of bile flow from the liver to the intestine, and accumulation of hydrophobic bile acids in the liver and plasma. As a consequence an inflammatory response evolves associated with increased apoptosis, oxidative stress, and eventually fibrosis. Cholestasis is associated with profound metabolic changes, alterations in the mitochondrial func...
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Primary biliary cirrhosis and primary sclerosing cholangitis are two most frequently encountered cholestatic condition in adults. Liver transplantation is an excellent option in patients who progress to end-stage liver disease. In these patients typical indications for liver transplantation are no different than in other conditions requiring transplantation. Liver transplantation however might ...
متن کاملManagement of Pruritus in Chronic Liver Disease
Background. There continues to be uncertainty on the ideal treatment of pruritus in chronic liver disease. The aim of this study was to gather the latest information on the evidence-based management of pruritus in chronic liver disease. Methodology. A literature search for pruritus in chronic liver disease was conducted using Pubmed and Embase database systems using the MeSH terms "pruritus," "...
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ژورنال
عنوان ژورنال: Almanac of Clinical Medicine
سال: 2017
ISSN: 2587-9294,2072-0505
DOI: 10.18786/2072-0505-2017-45-5-366-376